Recent publications

The ups and downs of growth hormone secretagogue receptor signaling.
Cornejo MP, Mustafá ER, Cassano D, Banères JL, Raingo J, Perello M.
FEBS J. 2021 Jan 18. doi: 10.1111/febs.15718. Online ahead of print.

The Intriguing Ligand-dependent and Ligand-independent Actions of the Growth Hormone Secretagogue Receptor on Reward-related Behaviors.
Cornejo MP, Mustafá ER, Barrile F, Cassano D, De Francesco PN, Raingo J, Perello M.
Neurosci Biobehav Rev. 2021 Jan;120:401-416. doi: 10.1016/j.neubiorev.2020.10.017. Epub 2020 Nov 4.

Growth hormone secretagogue receptor in dopamine neurons controls appetitive and consummatory behaviors towards high-fat diet in ad-libitum fed mice.
Cornejo MP, Barrile F, Cassano D, Aguggia JP, García Romero G, Reynaldo M, Andreoli MF, De Franceso PN, Perello M.
Psychoneuroendocrinology, 2020 May 22. 2020;119:104718. doi:10.1016/j.psyneuen.2020.104718

Plasma levels of ghrelin, des-acyl ghrelin and LEAP2 in children with obesity: correlation with age and insulin resistance.
Fittipaldi AS, Hernández J, Castrogiovanni D, Lufrano D, De Francesco PN, Garrido V, Vitaux P, Fasano MV, Fehrentz J, Fernández A, Andreoli MF, Perello M.
Eur J Endocrinol. 2020;182(2):165-175. doi:10.1530/EJE-19-0684

Development of a novel fluorescent ligand of growth hormone secretagogue receptor based on the N-Terminal Leap2 region.
Barrile F, M’Kadmi C, De Francesco PN, Cabral A, Gracía Romero G, Mustafá ER, Cantel S, Damian M, Mary S, Denoyelle S, Banéres J, Marie J, Raingo J, Fehrentz J, Perello M.
Mol Cell Endocrinol. 2019;498:110573. doi:10.1016/j.mce.2019.110573

Inter-individual Variability for High Fat Diet Consumption in Inbred C57BL/6 Mice.
De Francesco PN, Cornejo MP, Barrile F, Gracía Romero G, Valdivia S, Andreoli MF, Perello M.
Front Nutr. 2019;6:67. Published 2019 May 9. doi:10.3389/fnut.2019.00067

Brain accessibility delineates the central effects of circulating ghrelin.
Perello M, Cabral A, Cornejo MP, De Francesco PN, Fernandez G, Uriarte M. J Neuroendocrinol. 2019;31(7):e12677. doi:10.1111/jne.12677

Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice.
Fernandez G, Cabral A, Andreoli MF, Labarthe A, M’Kadmi C, Ramos JG, Marie J, Fehrentz JA, Epelbaum J, Tolle V, Perello M.
Endocrinology. 2018 Feb 1;159(2):1021-1034. doi: 10.1210/en.2017-03101.

Ghrelin Recruits Specific Subsets of Dopamine and GABA Neurons of Different Ventral Tegmental Area Sub-nuclei.
Cornejo MP, Barrile F, De Francesco PN, Portiansky EL, Reynaldo M, Perello M.
Neuroscience. 2018;392:107-120. doi:10.1016/j.neuroscience.2018.09.027.

Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract.
Cornejo MP, De Francesco PN, García Romero G, Portiansky EL, Zigman JM, Reynaldo M, Perello M.
Brain Struct Funct. 2018;223(7):3133-3147. doi:10.1007/s00429-018-1682-5

A simple strategy for culturing morphologically-conserved rat hypothalamic tanycytes.
De Francesco PN, Castrogiovanni D, Uriarte M, Frassa V, Agosti F, Raingo J, Perello M.
Cell Tissue Res. 2017 Apr 17. doi: 10.1007/s00441-017-2608-x. [Epub ahead of print]

Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice.
Fernandez G, Cabral A, Andreoli MF, Labarthe A, M’Kadmi C, Ramos JG, Marie J, Fehrentz J, Epelbaum J, Tolle V, Perello M.
Endocrinology. 2018;159(2):1021-1034. doi:10.1210/en.2017-03101

Is Ghrelin Synthesized in the Central Nervous System?
Cabral A, López Soto EJ, Epelbaum J, Perelló M.
Int J Mol Sci. 2017 Mar 15;18(3). pii: E638. doi: 10.3390/ijms18030638. Review.

Circulating Ghrelin Acts on GABA Neurons of the Area Postrema and Mediates Gastric Emptying in Male Mice.
Cabral A, Cornejo MP, Fernandez G, De Francesco PN, Garcia-Romero G, Uriarte M, Zigman JM, Portiansky E, Reynaldo M, Perello M.
Endocrinology. 2017 May 1;158(5):1436-1449. doi: 10.1210/en.2016-1815.